Helps with viral infections, rheumatism and influenza. Save the stomach - the only buffered aspirin with ph = 5.5 With rapid absorption in the intestine - immediate effect against pain and fever.

COMPOSITION: Acetylsalicylic acid 0.330 g

Ascorbic acid 0.200 g for one effervescent tablet of 3.501 g

PHARMACEUTICAL FORM: Effervescent tablet with score line

INDICATIONS: Helps with viral infections, rheumatism and influenza. Save the stomach - the only buffered aspirin with ph = 5.5

With rapid absorption in the intestine - immediate effect against pain and fever.

Therapeutic indications: Symptomatic treatment of mild to moderate pain and / or febrile conditions.

Posology and method of administration: Use only for adults and children weighing 30 kg or more (over 12 years). Oral administration

One effervescent tablet is completely dissolved in a glass of sweetened or plain water, milk or fruit juice and drunk immediately.

Regular application avoids fluctuations in pain or temperature. An interval of at least 4 hours is required between doses.

Due to the presence of vitamin C, it is advisable to avoid the use of irBapp C at the end of the day.

-Mild to moderate pain and / or fever

Adults: the maximum daily dose is 3 g of acetylsalicylic acid.

Recommended dose: one or two tablets of 330 mg as needed

repeated at intervals of 4 hours, not exceeding 9 effervescent tablets per day.

Elderly patient: the maximum daily dose is 2 g.

Recommended dose: one or two tablets of 330 mg, if necessary the dose is repeated at intervals of 4 hours, not exceeding 6 effervescent tablets per day.

Depots: the maximum daily dose in children is 50 mg / kg.

Recommended dose: children weighing between 30 and 50 lb (12 to 15 years): one tablet of 330 mg and, if necessary, the dose is repeated after 4 hours, not exceeding 6 effervescent tablets per day.

The approximate age in terms of weight is given only as a guide.

Contraindications:

- known allergy to salicylates and substances with similar activity, especially non-steroidal anti-inflammatory drugs

- active peptic ulcer

- any congenital or acquired hemorrhagic disease

- hemorrhagic risk

- kidney stones during the use of high doses of vitamin C (more than 1 g) -when used in analgesic, anti-inflammatory or anti-inflammatory doses (> 500 mg daily), this drug is contraindicated in and from the sixth month of pregnancy

- in combination with methotrexate, if the latter is used in doses exceeding 15 minutes per week

- use with oral anticoagulants is contraindicated when salicylates are used in high doses (> 3 g daily)

As a general rule, it should not be used in combination with:

- oral anticoagulants when salicylates are used in doses <3 g daily

- heparin

- ticlopidine

- uricosuric agents

- other non-steroidal anti-inflammatory drugs (for high doses of acetylsalicylic acid, ie (> 3 g daily in adults)

The use of this drug is not recommended during breast-feeding,

COMBINATIONS NOT RECOMMENDED:

- Oral anticoagulants

Increased risk of bleeding (suppression of thromboid function and damage to the gastroduodenal mucosa).

Salicylates in low doses: monitoring is required, especially at the time of bleeding.

including salicylates (3 g or more per day in adults)

Increased risk of ulceration and gastrointestinal bleeding (additive

synergy)

-Heparin

Increased risk of bleeding (suppression of platelet function and damage to the gastrointestinal mucosa by salicylates).

BREAST-FEEDING: Acetylsalicylic acid is not recommended during breast-feeding as it passes into breast milk.

EFFECTS ON THE ABILITY TO DRIVE AND USE MACHINES: no data available

SIDE EFFECTS:

- Effects on the central nervous system: tinnitus; feeling of reduced hearing; headache, which is usually a sign of an overdose

- Gastrointestinal effects: stomach ulcers; gastrointestinal bleeding that is visible (hematemesis, melena, etc.) or occult and cause iron deficiency anemia. The higher the doses, the greater the frequency of bleeding.

- Haematological effects: haemorrhagic syndrome (nosebleeds, bleeding gums, purpura, etc.) with prolonged bleeding time. The effect lasts from 4 to 8 days after stopping the use of acetylsalicylic acid. May cause a risk of bleeding in patients undergoing surgery.

- Hypersensitivity reactions: sensitizing reactions: Quincke's edema, urticaria, asthma, anaphylactic reactions.

- Others: abdominal pain

- High doses of vitamin C (over 1 g) can cause the formation of oxalate stones and uric acid stones in certain individuals, and may increase the hemolysis of patients with ARI deficiency in forms with chronic hemolysis.

Overdose: Overdose is observed in elderly patients and especially in young children (therapeutic overdose or frequently observed accidental poisoning) which can be fatal. Clinical symptoms:

• moderate intoxication: tinnitus, hearing loss, headache, vertigo, nausea are symptoms of overdose and they can be controlled by reducing the dose.

• severe intoxication: fever, hyperventilation, ketosis, respiratory alkalosis, metabolic acidosis, circulatory collapse, respiratory failure, significant hypoglycaemia.

Treatment:

• Immediate hospital admission

• rapid elimination by gastric lavage of ingested quantities

• monitoring of the alkaline-acid balance

• forced alkaline diuresis and hemodialysis or peritoneal dialysis if necessary

• symptomatic treatment

Shelf life: 3 years

Special precautions for storage: Store below 25 ° C.

Manufacturer: UPSA